Thursday, June 6, 2013

Mesothelioma: Different Ways to Cure It- Is Mesothelioma Curable

As their label implies, potentially healing procedures are done with the intent to cure patients of the disease. The main objective of these procedures is the entire removal of gross disease. Residual microscopic disease is usually blasted away with the use of adjuvant therapy, which usually takes the kind of a combination of chemo & radiotherapy. Studies have shown that a trimodality approach that combines surgical procedure with radiation & chemotherapy or with other new approaches such as gene therapy, photodynamic therapy or immunotherapy are more effective at arriving a cure.

Treatment approaches to malignant mesothelioma -Is Mesothelioma Curable

consist of healing procedures & practices of palliative care.

A more radical approach that can be used to potentially cure pleural mesothelioma is Extrapleural Pneumonectomy. Since this is a more radical procedure, more expertise is also necessary of the surgeons. Patients must meet a sure set of criteria before extrapleural pneumonectomy can be performed on them. The criteria include a Karnofsky Performance Status score of >70, adequate kidney & liver functions, within normal electrocardiogram & echocardiography results, adequate pulmonary function tests, limitation of the disease to the ipsilateral hemithorax with no involvement of either the diaphragm, heart or chest wall, & age of the patient. The age is not given as much weight as the general functional status of the patient.

An example of a potentially healing procedure-Is Mesothelioma Curable
 that is done for pleural mesothelioma is pleurectomy or decortication. This is usually done on patients who are in stages I & II of the malignant mesothelioma. Removal of all gross tumor is tried with this procedure. If the entire removal of the tumor necessitates the removal of the lung, then a concurrent pneumonectomy is also performed.

For patients with the more advanced stages of malignant mesothelioma for which the aforementioned healing approaches are not warranted, treatment ought to be geared towards the use of palliative procedures.

For peritoneal mesothelioma, a cytoreductive surgical procedure is performed to possibly effect a cure. As with the approaches used for pleural mesothelioma, this is done with the objective of removing all gross tumor. Cytoreductive surgical procedure is usually combined with Intraperitoneal Hyperthermic Chemotherapy (IPHC) which is aimed wipe out any remaining microscopic cancer cells.

A pleuroperitoneal shunt is another palliative procedure that involves catheter placement, threading it under the patient's skin from the pleural to the peritoneal cavity. This is not a popular palliative treatment option because of the feasible obstruction of the catheter and seeding of tumor in various cavities.

Palliative procedures are aimed at relieving the signs brought about by the disease in the hopes of improving the patient's quality of life. Chest Tube drainage and pleurodesis is a common palliative treatment employed to relieve liquid buildup or effusion in the chest cavity. Since malignant pleural effusions are usually persistent, after the preliminary drainage, pleurodesis is often performed to permanently close the pleural space and prevent the liquid from re-accumulating. Talc powder or other sclerosing agents are used as adhesives.

Thoracoscopy with pleurodesis -Is Mesothelioma Curable
is another palliative procedure with a similar strategy. Both these procedures can only be completed if the tumor has not yet encased the lungs. The unrestricted expansive capacity of the lungs has to be still intact for these procedures to work. In cases where in the disease is effecting a restriction on the lung's expansion, a pleurectomy is the most effective treatment means to control pleural effusion.

The choice of treatment options-Is Mesothelioma Curable
 for malignant mesothelioma is Dependant on the patient's stage of the disease at diagnosis. Prompt recognition of signs and timely diagnosis are still requisite before these treatment options can be instituted.

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